Nature:死无对证的时代落幕

2022-02-14 12:06:03 来源:
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日和,冷泉大港科学研究室(CSHL)研究课题团队在Nature上发表关于脑部切片的研究课题报道,称通过脑部切片可以准确地判断灵长类两栖动物生前所不感兴趣的行为基础训练。这项研究课题为人们进一步解释脑部的深造和梦境解码机制提供了新角度。

感觉的决定是基于感觉皮层脊髓元的活动,但是生物体如何深造将这种活动裂解为恰当的行为仍然有待为了让。研究课题医护人员在灵长类两栖动物当中研究课题沙哑线索裂解为行动的过程。首先,对灵长类两栖动物进行基础训练,使其对特定的沙哑与奖赏建立条件反射。灵长类两栖动物但会根据沙哑的发生变化,在盒子之中寻找奖赏日常用品。并在灵长类两栖动物不感兴趣基础训练的时候,检测脊髓连接的切变。发现完全相同的两栖动物不感兴趣基础训练的情况,听觉纹状体但会出现一个活性温度梯度。

研究课题医护人员推论,在此一新毕竟必须通过死后的脑部切片来判断灵长类两栖动物经历过什么样的基础训练。进一步的科学研究验证这种推断是值得注意的,这也标志着新梦境解码的密码被破解,代表特定梦境的突触能被精确定位。

研究课题医护人员坚称他们迫不及待地要将这种方法运用于到向视觉这种更为有用的深造形式和感觉系统当中去。如果必须在不同的感觉系统当中重大突破运用于,这就意味着那些死无对证的时代就此终结。类似这种解读脑部的个人信息的科学研究并非由此开创,Mary Lou Jepsen是进制辨识行业内的顶级专家,她研究课题如何将生命体最具创造力的想法辨识到屏幕上。在她令人惊叹的演讲当中,她将进制和脑部这两方面的爱好相辅相成于两项尖端的脑研究课题新项目当中,它们不太可能为我们解释生命体如何思考以及在思考什么指明新方向。

生物谷推荐读者英文原文:

selecive corticostriatal plasticity during acquisition of an auditory discrimination task

Perceptual decisions are based on the activity of sensory cortical neurons, but how organisms learn to transform this activity into appropriate actions remains unknown. Projections from the auditory cortex to the auditory striatum carry information that drives decisions in an auditory frequency discrimination task1. To assess the role of these projections in learning, we developed a channelrhodopsin-2-based assay to probe selecively for synaptic plasticity associated with corticostriatal neurons representing different frequencies. Here we report that learning this auditory discrimination preferentially potentiates corticostriatal synapses from neurons representing either high or low frequencies, depending on reward contingencies. We observe frequency-dependent corticostriatal potentiation in vivo over the course of training, and in vitro in striatal brain slices. Our findings suggest a model in which the corticostriatal synapses made by neurons tuned to different features of the sound are selectively potentiated to enable the learned transformation of sound into action.

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